‘Of course, that's about appropriate. I search for a physical comprehension of Organic programs inside a bottom-up way. I do think you can distinguish 3 strains of study in my team at the moment. The initial problems chromosome structure: How would you have a metre-extensive DNA polymer folded and organised in such a microscopic cell? We now have created visualisation tactics that make it possible for us to check how, for instance, SMC proteins loop DNA (movie on Youtube) so as to Establish up chromosomes.
Springer Mother nature or its licensor retains exceptional legal rights to this short article below a publishing agreement With all the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript Variation of this article is only governed through the phrases of this sort of publishing agreement and applicable regulation.
As a human being, I hold the biblical assignment to take a look at and use all the things in creation for the benefit of my neighbour. I will not knowledge any conflict among faith and science. On the contrary, my faith stimulates me to perform science, to generally be open-minded on earth.’
I'm able to rarely picture how I, to be a geneticist, would be able to find out elementary physics, not to mention contend at the best. How did you go over it?
2015, discovery that condensin is often a really adaptable protein construction; and 1st detection of DNA knots utilizing nanopores
The coiled-coil on the human Rad50 DNA restore protein incorporates distinct segments of elevated adaptability
Considering that 2000 he moved to single-molecule biophysics and nanobiology, with study from DNA supercoiling studies of nucleosomes and DNA maintenance proteins to DNA translocation by nanopores. Just lately his analysis has focused on researching cell division with bacteria on chip, while his top curiosity is in the course of acknowledging synthetic cells.
Atomic power microscopy demonstrates that vaccinia topoisomerase IB generates filaments on DNA in a cooperative trend
This "Cited by" count contains citations to the next article content in Scholar. The ones marked * could be unique within the article within the profile.
But carbon nanotubes have remained a investigate subject of sizeable desire to lots of. Certainly, the outlook on employing carbon nanotubes to create useful products, in regions including radio-frequency electronics, digital electronics and versatile electronics, remains dazzling.
‘The concept there is such a issue to be a commencing, a large bang, is previously a fascinating signpost to look at that there was a creator. But much more generally, and on the basis of pure rationality, I also arrive at a Christian interpretation of actuality. An atheistic worldview can be a naturalistic worldview: essentially, there are actually only atoms and normal forces that we could evaluate.
‘That worries the artificial mobile, as Section of the Dutch BaSyC initiative. Craig Venter appeared major-down in Individuals days and discovered about five hundred genes that happen to be minimally expected for the operating mobile. We want to appear base-up: how do we transfer from the handful of ceesdekker.net molecules to an entire Organic program?
2005, discovery from the system of DNA uncoiling by topoisomerase enzymes; discovery of long-selection conformational changes in Mre11/DNA mend complexes; and first power measurements with a DNA molecule within a nanopore
The biophysicist from Delft – who has long been One of the more cited scientists from the Netherlands for years – takes his obligation to lead for the rationalization and popularisation of his get the job done for the border of physics and biology exceptionally significantly and routinely seems while in the media; Otherwise to discuss his operate, then about the connection amongst science and his Christian faith.